ABCA1 ABCA1
ABCA1 (ABCA1): 88 variants described, covering trait, health risk, nutrition.
Which ABCA1 variants does Orviva describe?
- rs2245793 Health risk imported
- C allele associated with increased Cholesterol levels (UKB data field 30690) (β=0.029). [GWAS Catalog]
- rs2740488 Nutrition imported
- A allele associated with increased Total cholesterol levels (β=0.066). [GWAS Catalog]
- rs4149307 Nutrition imported
- C allele associated with decreased risk of high density lipoprotein cholesterol (HDLC, mean, inv-norm transformed) (OR=0.10). [GWAS Catalog]
85 further ABCA1 variants in the knowledge base have only a brief annotation and are not listed here.
See your own ABCA1 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my ABCA1 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my ABCA1 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.