ABCG8 ATP-binding cassette subfamily G member 8
ABCG8 (ATP-binding cassette subfamily G member 8): 24 variants described, covering health risk, nutrition, trait.
Which ABCG8 variants does Orviva describe?
- rs11887534 Health risk
- ABCG8 D19H homozygous. Significantly increased gallstone risk (2-3x).
- rs4299376 Health risk imported
- T allele associated with increased Total cholesterol levels (β=0.065). [GWAS Catalog]
22 further ABCG8 variants in the knowledge base have only a brief annotation and are not listed here.
See your own ABCG8 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my ABCG8 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my ABCG8 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.