APOE - APOC1 APOE - APOC1
APOE - APOC1 (APOE - APOC1): 12 variants described, covering health risk, nutrition, trait.
Which APOE - APOC1 variants does Orviva describe?
- rs10414043 Health risk imported
- A allele associated with decreased risk of Cerebral amyloid deposition (PET imaging) (OR=0.15). [GWAS Catalog]
- rs1065853 Nutrition imported
- G allele associated with decreased risk of LDL cholesterol (OR=0.60). [GWAS Catalog]
- rs1081105 Health risk imported
- C allele associated with substantially increased risk of Alzheimer's disease or family history of Alzheimer's disease (OR=32.50). [GWAS Catalog]
- rs483082 Nutrition imported
- G allele associated with increased Triglyceride levels (β=0.086). [GWAS Catalog]
- rs7256200 Trait imported
- G allele associated with increased Total lipid levels in HDL (β=0.058). [GWAS Catalog]
- rs72654473 Nutrition imported
- C allele associated with decreased risk of triglyceride (maximum, inv-norm transformed) (OR=0.14). [GWAS Catalog]
6 further APOE - APOC1 variants in the knowledge base have only a brief annotation and are not listed here.
See your own APOE - APOC1 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my APOE - APOC1 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my APOE - APOC1 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.