BDNF Brain-derived neurotrophic factor
BDNF (Brain-derived neurotrophic factor): 24 variants described, covering trait, drug response, health risk, nutrition.
Which BDNF variants does Orviva describe?
- rs6265 Trait
- BDNF Val66Met Met/Met. Reduced activity-dependent BDNF secretion; may affect memory and neuroplasticity. Common in East Asian populations.
- rs962369 Health risk imported
- T allele associated with increased Body mass index (β=0.021). [GWAS Catalog]
22 further BDNF variants in the knowledge base have only a brief annotation and are not listed here.
See your own BDNF genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my BDNF variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my BDNF variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.