CHRNA3 CHRNA3
CHRNA3 (CHRNA3): 20 variants described, covering health risk, trait, nutrition.
Which CHRNA3 variants does Orviva describe?
- rs1051730 Health risk imported
- T allele associated with slightly increased risk of Lung cancer in ever smokers (OR=1.34). [GWAS Catalog]
- rs12914385 Trait imported
- T allele associated with increased Cigarettes smoked per day (current) (β=0.014). [GWAS Catalog]
- rs28681284 Trait imported
- T allele associated with increased Smoking behaviour (cigarettes smoked per day) (β=0.049). [GWAS Catalog]
- rs55676755 Trait imported
- G allele associated with marginally increased risk of Chronic obstructive pulmonary disease (OR=1.11). [GWAS Catalog]
- rs8040868 Health risk imported
- C allele associated with increased Cigarettes smoked per day (past) (β=0.044). [GWAS Catalog]
15 further CHRNA3 variants in the knowledge base have only a brief annotation and are not listed here.
See your own CHRNA3 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my CHRNA3 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my CHRNA3 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.