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F2 Coagulation factor II (prothrombin)

F2 (Coagulation factor II (prothrombin)): 8 variants described, covering health risk, nutrition.

1 curated variant

Which F2 variants does Orviva describe?

rs1799963 Health risk
Prothrombin G20210A homozygous. Significantly increased thrombosis risk.

7 further F2 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.