FADS1, FADS2 FADS1, FADS2
FADS1, FADS2 (FADS1, FADS2): 15 variants described, covering nutrition, health risk, trait, drug response.
Which FADS1, FADS2 variants does Orviva describe?
- rs174544 Nutrition imported
- C allele associated with increased Cholesteryl esters to total lipids ratio in medium HDL (β=0.049). [GWAS Catalog]
- rs174553 Health risk imported
- A allele associated with decreased risk of Ratio of monounsaturated fatty acids to total fatty acids (OR=0.15). [GWAS Catalog]
- rs174555 Nutrition imported
- T allele associated with decreased risk of Plasma omega-6 polyunsaturated fatty acid levels (dihomo-gamma-linolenic acid) (OR=0.39). [GWAS Catalog]
- rs174556 Health risk imported
- C allele associated with increased low density lipoprotein cholesterol (LDLC, mean, inv-norm transformed) (β=0.027). [GWAS Catalog]
- rs4564341 Nutrition imported
- A allele associated with increased Triacylglycerol(56:6)_[M+NH4]1+ levels (β=0.040). [GWAS Catalog]
- rs968567 Nutrition imported
- T allele associated with increased Plasma 1-palmitoyl-2-dihomo-linolenoyl-GPC (16:0/20:3n3 or 6)* levels in chro... (β=0.086). [GWAS Catalog]
9 further FADS1, FADS2 variants in the knowledge base have only a brief annotation and are not listed here.
See your own FADS1, FADS2 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my FADS1, FADS2 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my FADS1, FADS2 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.