FTO Fat mass and obesity-associated (alpha-ketoglutarate-dependent dioxygenase)

Which FTO variants does Orviva describe?

rs9939609 Health risk

FTO risk variant homozygous. Associated with increased BMI and obesity risk (1.67x odds).

rs11075990 Trait imported

G allele associated with slightly increased risk of Body mass index (OR=1.35). [GWAS Catalog]

rs12149832 Trait imported

A allele associated with increased Body mass index (SNP x SNP interaction) (β=0.073). [GWAS Catalog]

rs17817964 Health risk imported

T allele associated with increased Body mass index (adult) (β=0.069). [GWAS Catalog]

rs62033408 Health risk imported

A allele associated with substantially increased risk of Alcohol use disorder (consumption score) (OR=9.08). [GWAS Catalog]

rs62048402 Nutrition imported

G allele associated with increased Hypertension (PheCode 401) (β=0.085). [GWAS Catalog]

rs7193144 Health risk imported

T allele associated with increased Body mass index (β=0.073). [GWAS Catalog]

rs7202116 Trait imported

G allele associated with increased Body mass index (β=0.036). [GWAS Catalog]

rs72805613 Health risk imported

G allele associated with increased BMI x meat diet interaction (β=0.043). [GWAS Catalog]

rs8047587 Trait imported

G allele associated with increased Sleep duration (β=0.018). [GWAS Catalog]

rs9926289 Nutrition imported

A allele associated with substantially increased risk of Alcohol use disorder (OR=7.17). [GWAS Catalog]

rs9930333 Health risk imported

G allele associated with increased Body mass index (β=0.084). [GWAS Catalog]

127 further FTO variants in the knowledge base have only a brief annotation and are not listed here.