GC GC vitamin D binding protein
GC (GC vitamin D binding protein): 34 variants described, covering nutrition; nutrient interactions.
Which GC variants does Orviva describe?
- rs2282679 Nutrition
- Significantly lower vitamin D binding protein levels. Higher supplementation needs.
- rs7041 Nutrition
- GC Asp432Glu homozygous. Lower vitamin D binding protein affinity; may need higher vitamin D intake.
32 further GC variants in the knowledge base have only a brief annotation and are not listed here.
Which nutrients interact with GC variants?
- vitamin D3 strong evidence
- GC/DBP variants reduce vitamin D binding protein levels, lowering circulating 25-OH-VD
Often considered alongside: vitamin K2, magnesium.
Lab markers that reflect this pathway: 25-OH-VD, CALCIUM.
Dose ranges are deliberately not shown here; they depend on genotype, current levels and other medicines.
See your own GC genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my GC variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my GC variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.