Orviva

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GLIS3 GLIS3

GLIS3 (GLIS3): 60 variants described, covering trait, health risk, nutrition, drug response.

3 imported

Which GLIS3 variants does Orviva describe?

rs10758593 Health risk imported
A allele associated with decreased risk of Gestational diabetes mellitus (OR=0.18). [GWAS Catalog]
rs10758594 Health risk imported
A allele associated with increased Insomnia (β=0.005). [GWAS Catalog]
rs4741961 Health risk imported
C allele associated with increased Systolic blood pressure (MTAG) (β=0.013). [GWAS Catalog]

57 further GLIS3 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.