HFE Homeostatic iron regulator

HFE (Homeostatic iron regulator): 2 variants described, covering nutrition.

2 curated variants

Which HFE variants does Orviva describe?

rs1799945 Nutrition: HFE H63D homozygous. Moderately increased iron absorption; mild hemochromatosis risk.
rs1800562 Nutrition: HFE C282Y homozygous. High risk for hereditary hemochromatosis (iron overload). Monitor iron/ferritin levels; avoid iron supplements.

See your own HFE genotypes
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Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.