HMGCR HMGCR
HMGCR (HMGCR): 15 variants described, covering health risk, drug response, nutrition.
Which HMGCR variants does Orviva describe?
- rs4704210 Nutrition imported
- C allele associated with increased Cholesteryl esters in very small VLDL (UKB data field 23520) (β=0.057). [GWAS Catalog]
14 further HMGCR variants in the knowledge base have only a brief annotation and are not listed here.
See your own HMGCR genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my HMGCR variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my HMGCR variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.