Orviva

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IFNL4 IFNL4

IFNL4 (IFNL4): 4 variants described, covering drug response, health risk.

1 imported

Which IFNL4 variants does Orviva describe?

rs11322783 Drug response imported
Genotype GG is associated with decreased response to ribavirin and sofosbuvir in people with Hepatitis C, Chronic as compared to genotypes G/TT + TT/TT.

3 further IFNL4 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.