IRF4 Interferon regulatory factor 4
IRF4 (Interferon regulatory factor 4): 11 variants described, covering health risk, ancestry, trait.
Which IRF4 variants does Orviva describe?
- rs12203592 Ancestry
- IRF4 variant. Strong association with blue eyes, blond hair, fair skin, and freckling in Europeans.
- rs3778607 Health risk imported
- A allele associated with marginally increased risk of Blond vs. brown/black hair color (OR=1.08). [GWAS Catalog]
9 further IRF4 variants in the knowledge base have only a brief annotation and are not listed here.
See your own IRF4 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my IRF4 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my IRF4 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.