LPA LPA
LPA (LPA): 44 variants described, covering drug response, trait, health risk, nutrition.
Which LPA variants does Orviva describe?
- rs140570886 Nutrition imported
- C allele associated with decreased risk of Cholesteryl Esters to Total Lipids in Large VLDL percentage (OR=0.40). [GWAS Catalog]
- rs6938647 Nutrition imported
- C allele associated with increased Phospholipids in small LDL (β=0.030). [GWAS Catalog]
- rs73596816 Nutrition imported
- A allele associated with decreased risk of Free cholesterol to total lipids in chylomicrons and extremely large VLDL per... (OR=0.15). [GWAS Catalog]
41 further LPA variants in the knowledge base have only a brief annotation and are not listed here.
See your own LPA genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my LPA variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my LPA variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.