LRP5 LDL receptor-related protein 5
LRP5 (LDL receptor-related protein 5): 16 variants described, covering health risk, trait.
Which LRP5 variants does Orviva describe?
- rs3736228 Health risk
- LRP5 A1330V homozygous. Reduced bone mineral density; increased fracture and osteoporosis risk.
- rs314779 Trait imported
- T allele associated with increased Height (baseline) (β=0.014). [GWAS Catalog]
- rs4988321 Health risk imported
- A allele associated with increased Hip index (β=0.042). [GWAS Catalog]
13 further LRP5 variants in the knowledge base have only a brief annotation and are not listed here.
See your own LRP5 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my LRP5 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my LRP5 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.