MC1R Melanocortin 1 receptor
MC1R (Melanocortin 1 receptor): 18 variants described, covering trait, drug response, health risk.
Which MC1R variants does Orviva describe?
- rs1805007 Trait
- MC1R R151C homozygous. Red hair, fair skin, freckling. Increased melanoma and skin cancer risk.
- rs1805008 Trait
- MC1R R160W homozygous. Strong association with red hair, fair skin, and freckling.
16 further MC1R variants in the knowledge base have only a brief annotation and are not listed here.
See your own MC1R genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my MC1R variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my MC1R variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.