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NAT2 N-acetyltransferase 2

NAT2 (N-acetyltransferase 2): 11 variants described, covering drug response, health risk; CPIC pharmacogenomic guidance available.

NAT2 and medicines

NAT2 is a pharmacogene with CPIC guidance. Star alleles, metaboliser phenotypes and the drugs affected are on the NAT2 pharmacogenomics page.

Which NAT2 variants does Orviva describe?

No variant with a full description yet.

11 further NAT2 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.