NQO1 NQO1
NQO1 (NQO1): 3 variants described, covering health risk, drug response; nutrient interactions.
Which NQO1 variants does Orviva describe?
- rs2917677 Health risk imported
- C allele associated with increased Body mass index (β=0.022). [GWAS Catalog]
2 further NQO1 variants in the knowledge base have only a brief annotation and are not listed here.
Which nutrients interact with NQO1 variants?
- ubiquinol moderate evidence
- NQO1 Pro187Ser reduces quinone reductase activity; ubiquinol bypasses the need for NQO1-mediated reduction
Often considered alongside: NAC, glutathione.
Dose ranges are deliberately not shown here; they depend on genotype, current levels and other medicines.
See your own NQO1 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my NQO1 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my NQO1 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.