OCA2 OCA2 melanosomal transmembrane protein
OCA2 (OCA2 melanosomal transmembrane protein): 64 variants described, covering trait, health risk, ancestry.
Which OCA2 variants does Orviva describe?
- rs1800414 Ancestry
- OCA2 His615Arg. Associated with lighter skin in East Asian populations.
- rs121918166 Health risk imported
- T allele associated with substantially increased risk of Blond vs. brown/black hair color (OR=5.94). [GWAS Catalog]
62 further OCA2 variants in the knowledge base have only a brief annotation and are not listed here.
See your own OCA2 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my OCA2 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my OCA2 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.