PEMT Phosphatidylethanolamine N-methyltransferase
PEMT (Phosphatidylethanolamine N-methyltransferase): 47 variants described, covering health risk, trait, nutrition.
Which PEMT variants does Orviva describe?
- rs12325817 Nutrition
- PEMT variant homozygous. Increased dietary choline requirement; risk of choline deficiency on low-choline diets.
- rs1109859 Trait imported
- G allele associated with increased Waist-to-hip ratio adjusted for BMI (β=0.025). [GWAS Catalog]
- rs11656215 Trait imported
- C allele associated with increased Hip index (β=0.016). [GWAS Catalog]
- rs4646359 Trait imported
- T allele associated with increased Height (β=0.019). [GWAS Catalog]
43 further PEMT variants in the knowledge base have only a brief annotation and are not listed here.
See your own PEMT genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my PEMT variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my PEMT variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.