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PEPD PEPD

PEPD (PEPD): 64 variants described, covering trait, health risk, nutrition.

5 imported

Which PEPD variants does Orviva describe?

rs10425465 Trait imported
G allele associated with increased Waist-hip index (β=0.028). [GWAS Catalog]
rs153701 Health risk imported
T allele associated with increased Waist circumference adjusted for body mass index (β=0.023). [GWAS Catalog]
rs3786920 Health risk imported
T allele associated with increased Gluteofemoral adipose tissue volumes (adjusted for BMI and height) (β=0.051). [GWAS Catalog]
rs4805881 Health risk imported
C allele associated with increased Sex hormone-binding globulin levels adjusted for BMI (β=0.009). [GWAS Catalog]
rs57457691 Trait imported
C allele associated with increased Body mass index (β=0.018). [GWAS Catalog]

59 further PEPD variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.