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PTPN22 Protein tyrosine phosphatase non-receptor type 22

PTPN22 (Protein tyrosine phosphatase non-receptor type 22): 3 variants described, covering health risk.

1 curated variant

Which PTPN22 variants does Orviva describe?

rs6679677 Health risk
Increased risk for rheumatoid arthritis, type 1 diabetes, and other autoimmune conditions.

2 further PTPN22 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.