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R3HDM2 R3HDM2

R3HDM2 (R3HDM2): 33 variants described, covering health risk, trait, drug response, nutrition.

4 imported

Which R3HDM2 variants does Orviva describe?

rs11172181 Health risk imported
T allele associated with increased Serum urate levels (β=0.069). [GWAS Catalog]
rs11613352 Nutrition imported
C allele associated with increased Triglycerides (β=0.040). [GWAS Catalog]
rs540730 Health risk imported
T allele associated with increased Sex hormone-binding globulin levels adjusted for BMI (β=0.018). [GWAS Catalog]
rs7964492 Drug response imported
A allele associated with marginally increased risk of Gout (OR=1.15). [GWAS Catalog]

29 further R3HDM2 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.