Orviva

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SORL1 SORL1

SORL1 (SORL1): 7 variants described, covering nutrition, health risk, trait.

1 imported

Which SORL1 variants does Orviva describe?

rs11218343 Health risk imported
T allele associated with substantially increased risk of Alzheimer's disease or educational attainment (pleiotropy) (OR=47.98). [GWAS Catalog]

6 further SORL1 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.