TCN2 TCN2
TCN2 (TCN2): 10 variants described, covering nutrition, trait, health risk; nutrient interactions.
Which TCN2 variants does Orviva describe?
No variant with a full description yet.
10 further TCN2 variants in the knowledge base have only a brief annotation and are not listed here.
Which nutrients interact with TCN2 variants?
- methylcobalamin moderate evidence
- TCN2 C776G reduces transcobalamin II binding efficiency, impairing cellular B12 delivery
Often considered alongside: methylfolate.
Lab markers that reflect this pathway: B12, HCY, MMA.
Dose ranges are deliberately not shown here; they depend on genotype, current levels and other medicines.
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my TCN2 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.