TOMM40 TOMM40
TOMM40 (TOMM40): 40 variants described, covering trait, health risk, drug response.
Which TOMM40 variants does Orviva describe?
- rs10119 Trait imported
- G allele associated with decreased risk of Vascular dementia (OR=0.33). [GWAS Catalog]
- rs157581 Health risk imported
- T allele associated with increased Aging (β=0.016). [GWAS Catalog]
- rs184017 Health risk imported
- T allele associated with increased Metabolic syndrome (β=0.092). [GWAS Catalog]
- rs2075650 Health risk imported
- G allele associated with significantly increased risk of Alzheimer's disease (OR=2.53). [GWAS Catalog]
- rs34404554 Trait imported
- G allele associated with decreased risk of Cerebral amyloid deposition (PET imaging) (OR=0.13). [GWAS Catalog]
- rs71352238 Trait imported
- C allele associated with decreased risk of Cerebral amyloid deposition (PET imaging) (OR=0.12). [GWAS Catalog]
34 further TOMM40 variants in the knowledge base have only a brief annotation and are not listed here.
See your own TOMM40 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my TOMM40 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my TOMM40 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.