UGT1A1 UDP glucuronosyltransferase 1A1
UGT1A1 (UDP glucuronosyltransferase 1A1): 3 variants described, covering drug response.
Which UGT1A1 variants does Orviva describe?
- rs4148323 Drug response imported
- Homozygous risk allele (A). Associated with: BILIRUBIN, SERUM LEVEL OF, QUANTITATIVE TRAIT LOCUS 1; phenotype not specified; CRIGLER-NAJJAR SYNDROME, TYPE II
2 further UGT1A1 variants in the knowledge base have only a brief annotation and are not listed here.
See your own UGT1A1 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my UGT1A1 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my UGT1A1 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.