VDR Vitamin D receptor
VDR (Vitamin D receptor): 27 variants described, covering nutrition, health risk, drug response; nutrient interactions.
Which VDR variants does Orviva describe?
- rs1544410 Nutrition
- VDR BsmI bb genotype. Altered vitamin D receptor function; may need higher vitamin D intake for bone health.
26 further VDR variants in the knowledge base have only a brief annotation and are not listed here.
Which nutrients interact with VDR variants?
- vitamin D3 strong evidence
- VDR variants reduce receptor efficiency, requiring higher vitamin D levels for adequate signaling
Often considered alongside: vitamin K2, magnesium.
Lab markers that reflect this pathway: 25-OH-VD, CALCIUM, PTH.
Dose ranges are deliberately not shown here; they depend on genotype, current levels and other medicines.
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my VDR variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.