rs13214872 RPL3P2 - WASF5P
G allele associated with moderately increased risk of Psoriasis or type 2 diabetes (trans-disease meta-analysis) (OR=1.67). [GWAS Catalog]
What is rs13214872?
rs13214872 is a single-nucleotide polymorphism (SNP) in the RPL3P2 - WASF5P gene. Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as GG. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.
What does each rs13214872 genotype mean?
| Genotype | Association | What the evidence says | Confidence |
|---|---|---|---|
| GG | elevated | G allele associated with moderately increased risk of Psoriasis or type 2 diabetes (trans-disease meta-analysis) (OR=1.67). [GWAS Catalog] | 95% |
Is rs13214872 on 23andMe and AncestryDNA chips?
Chip coverage is not recorded for this variant. Orviva reports it when a raw-data file contains it directly or via a well-correlated proxy SNP, and says so when it does not.
Sources
- PubMed 33385400
- GWAS Catalog
- GCST011991
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What is my genotype at rs13214872 and what does it mean for me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.