rs17822931 ABCC11
Wet earwax type. Also associated with typical body odor.
What is rs17822931?
rs17822931 is a single-nucleotide polymorphism (SNP) in the ABCC11 gene (ATP-binding cassette subfamily C member 11). Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as CC. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.
What does each rs17822931 genotype mean?
| Genotype | Association | What the evidence says | Confidence |
|---|---|---|---|
| CC | typical / lower | Wet earwax type. Also associated with typical body odor. | 92% |
| CT / TC | typical / lower | Wet earwax type (dominant trait). | 90% |
| TT | typical / lower | Dry earwax type. Reduced body odor. Common in East Asian populations. | 92% |
How common is the C allele of rs17822931?
Minor-allele frequency by population (gnomAD / 1000 Genomes):
| European | 88.0% |
|---|---|
| East Asian | 7.0% |
| African | 95.0% |
| South Asian | 70.0% |
| Admixed American | 60.0% |
| Global | 55.0% |
Is rs17822931 on 23andMe and AncestryDNA chips?
Yes — it is genotyped directly on 23andMe V3, 23andMe V4, 23andMe V5, AncestryDNA V1, AncestryDNA V2. Orviva reads it from a raw-data export without imputation.
Sources
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What is my genotype at rs17822931 and what does it mean for me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.