rs35225200 BANK1 - SLC39A8
A allele associated with increased Osteoarthritis, localized (PheCode 740.1) (β=0.096). [GWAS Catalog]
What is rs35225200?
rs35225200 is a single-nucleotide polymorphism (SNP) in the BANK1 - SLC39A8 gene. Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as AA. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.
What does each rs35225200 genotype mean?
| Genotype | Association | What the evidence says | Confidence |
|---|---|---|---|
| AA | typical | A allele associated with increased Osteoarthritis, localized (PheCode 740.1) (β=0.096). [GWAS Catalog] | 85% |
| CC | typical | C allele associated with increased Docosahexaenoic acid to total fatty acids percentage (β=0.020). [GWAS Catalog] | 75% |
Is rs35225200 on 23andMe and AncestryDNA chips?
Chip coverage is not recorded for this variant. Orviva reports it when a raw-data file contains it directly or via a well-correlated proxy SNP, and says so when it does not.
Sources
- PubMed 39024449
- GWAS Catalog
- GCST90476254
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What is my genotype at rs35225200 and what does it mean for me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.