rs3827760 EDAR
EDAR V370A variant. Associated with thicker hair, more sweat glands, shovel-shaped incisors. Nearly fixed in East Asian and Native American populations.
What is rs3827760?
rs3827760 is a single-nucleotide polymorphism (SNP) in the EDAR gene (Ectodysplasin A receptor). Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as CC. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.
What does each rs3827760 genotype mean?
| Genotype | Association | What the evidence says | Confidence |
|---|---|---|---|
| CC | typical / lower | EDAR V370A variant. Associated with thicker hair, more sweat glands, shovel-shaped incisors. Nearly fixed in East Asian and Native American populations. | 88% |
| TC / CT | typical / lower | One copy of EDAR East Asian variant. Intermediate phenotype. | 75% |
| TT | typical / lower | Ancestral EDAR variant. Common in European and African populations. | 78% |
How common is the C allele of rs3827760?
Minor-allele frequency by population (gnomAD / 1000 Genomes):
| European | 0.1% |
|---|---|
| East Asian | 87.0% |
| African | 0.1% |
| South Asian | 5.0% |
| Admixed American | 35.0% |
| Global | 25.0% |
Is rs3827760 on 23andMe and AncestryDNA chips?
Yes — it is genotyped directly on 23andMe V3, 23andMe V4, 23andMe V5, AncestryDNA V1, AncestryDNA V2. Orviva reads it from a raw-data export without imputation.
Sources
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What is my genotype at rs3827760 and what does it mean for me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.