rs4481887 OR2M7
Likely unable to smell asparagus metabolites in urine.
What is rs4481887?
rs4481887 is a single-nucleotide polymorphism (SNP) in the OR2M7 gene (Olfactory receptor 2M7). Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as AA. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.
What does each rs4481887 genotype mean?
| Genotype | Association | What the evidence says | Confidence |
|---|---|---|---|
| AA | typical / lower | Likely unable to smell asparagus metabolites in urine. | 68% |
| AG / GA | typical / lower | May have reduced ability to smell asparagus metabolites. | 65% |
| GG | typical / lower | Can likely smell asparagus metabolites in urine. | 68% |
How common is the A allele of rs4481887?
Minor-allele frequency by population (gnomAD / 1000 Genomes):
| European | 37.0% |
|---|---|
| East Asian | 25.0% |
| African | 30.0% |
| South Asian | 32.0% |
| Admixed American | 33.0% |
| Global | 32.0% |
Is rs4481887 on 23andMe and AncestryDNA chips?
Yes — it is genotyped directly on 23andMe V4, 23andMe V5, AncestryDNA V2. Orviva reads it from a raw-data export without imputation.
Sources
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What is my genotype at rs4481887 and what does it mean for me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.