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Learn · Variants · LINC02210-CRHR1

rs55938136 LINC02210-CRHR1

G allele associated with decreased risk of Alcohol frequency weekly (standard GWA) (OR=0.28). [GWAS Catalog]

Imported from public databases · not individually reviewed Trait · Risk / effect allele: A · dbSNP

What is rs55938136?

rs55938136 is a single-nucleotide polymorphism (SNP) in the LINC02210-CRHR1 gene. Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as GG. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.

What does each rs55938136 genotype mean?

GenotypeAssociationWhat the evidence saysConfidence
GGtypical / lowerG allele associated with decreased risk of Alcohol frequency weekly (standard GWA) (OR=0.28). [GWAS Catalog]80%
AAincreasedA allele associated with increased Hand grip strength (baseline) (β=0.014). [GWAS Catalog]75%

Is rs55938136 on 23andMe and AncestryDNA chips?

Chip coverage is not recorded for this variant. Orviva reports it when a raw-data file contains it directly or via a well-correlated proxy SNP, and says so when it does not.

Sources

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.