rs72921001 OR6A2
OR6A2 variant homozygous. Strong perception of soapy taste in cilantro/coriander.
What is rs72921001?
rs72921001 is a single-nucleotide polymorphism (SNP) in the OR6A2 gene (Olfactory receptor 6A2 (coriander taste)). Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as AA. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.
What does each rs72921001 genotype mean?
| Genotype | Association | What the evidence says | Confidence |
|---|---|---|---|
| AA | typical / lower | OR6A2 variant homozygous. Strong perception of soapy taste in cilantro/coriander. | 72% |
| CA / AC | typical / lower | OR6A2 carrier. May perceive soapy taste in cilantro. | 68% |
| CC | typical / lower | Normal cilantro taste perception. | 72% |
How common is the A allele of rs72921001?
Minor-allele frequency by population (gnomAD / 1000 Genomes):
| European | 15.0% |
|---|---|
| East Asian | 10.0% |
| African | 8.0% |
| South Asian | 12.0% |
| Admixed American | 12.0% |
| Global | 12.0% |
Is rs72921001 on 23andMe and AncestryDNA chips?
Yes — it is genotyped directly on 23andMe V4, 23andMe V5, AncestryDNA V2. Orviva reads it from a raw-data export without imputation.
Sources
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What is my genotype at rs72921001 and what does it mean for me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.