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PhenoAge

Levine PhenoAge — 513 CpG clock trained against a composite of 9 aging biomarkers (e.g. albumin, CRP, WBC), giving a biological age calibrated to mortality and healthspan outcomes.

Curated · human-reviewed Epigenetic clocks

What is PhenoAge?

Levine PhenoAge — 513 CpG clock trained against a composite of 9 aging biomarkers (e.g. albumin, CRP, WBC), giving a biological age calibrated to mortality and healthspan outcomes.

What does a high or low PhenoAge mean?

A clock outputs a methylation age in years. On its own it is neither high nor low; what carries information is the gap to chronological age (see the matching age-acceleration indicator) and how the value moves between repeated samples.

References

  1. Levine et al. 2018 — An epigenetic biomarker of aging for lifespan and healthspan (Aging) — https://doi.org/10.18632/aging.101414

Epigenetic clocks are research-grade estimates with a test-retest noise of several years. A single result is a snapshot, not a verdict; trends over repeated samples are what carry information. For general education only — not a diagnosis or a substitute for medical advice.