CYP3A5 Cytochrome P450 3A5
CYP3A5 (Cytochrome P450 3A5): 4 variants described, covering drug response, health risk.
Which CYP3A5 variants does Orviva describe?
- rs776746 Drug response
- CYP3A5*1/*1 expresser. Rapid tacrolimus metabolism; higher dose needed for transplant patients.
3 further CYP3A5 variants in the knowledge base have only a brief annotation and are not listed here.
See your own CYP3A5 genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my CYP3A5 variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my CYP3A5 variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.