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DARC/ACKR1 Duffy antigen receptor for chemokines (ACKR1)

DARC/ACKR1 (Duffy antigen receptor for chemokines (ACKR1)): 1 variant described, covering ancestry.

1 curated variant

Which DARC/ACKR1 variants does Orviva describe?

rs2814778 Ancestry
Duffy-null phenotype. Provides resistance to P. vivax malaria. Nearly fixed in sub-Saharan African populations.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.