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FGFR2 Fibroblast growth factor receptor 2

FGFR2 (Fibroblast growth factor receptor 2): 21 variants described, covering health risk, trait.

1 curated variant 1 imported

Which FGFR2 variants does Orviva describe?

rs2981582 Health risk
FGFR2 variant associated with increased breast cancer risk (1.26x per allele).
rs2420946 Health risk imported
A allele associated with slightly increased risk of Breast cancer in BRCA2 mutation carriers (OR=1.27). [GWAS Catalog]

19 further FGFR2 variants in the knowledge base have only a brief annotation and are not listed here.

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.