G6PD Glucose-6-phosphate dehydrogenase
G6PD (Glucose-6-phosphate dehydrogenase): 4 variants described, covering drug response, health risk.
Which G6PD variants does Orviva describe?
- rs1050828 Drug response imported
- Homozygous risk allele (T). Associated with: Anemia, nonspherocytic hemolytic, due to g6pd deficiency; phenotype not specified; Direct bilirubin levels
- rs5030868 Drug response imported
- G6PD Mediterranean variant carrier. Severe G6PD deficiency. Rasburicase, primaquine, dapsone contraindicated.
2 further G6PD variants in the knowledge base have only a brief annotation and are not listed here.
See your own G6PD genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my G6PD variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my G6PD variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.