PPARG Peroxisome proliferator-activated receptor gamma

PPARG (Peroxisome proliferator-activated receptor gamma): 68 variants described, covering trait, health risk, nutrition, drug response.

1 curated variant 8 imported

Which PPARG variants does Orviva describe?

rs1801282 Health risk: May have altered insulin sensitivity. PPARG Pro12Ala affects adipocyte differentiation.
rs11709077 Trait imported: A allele associated with increased Body mass index (MTAG) (β=0.019). [GWAS Catalog]
rs13083375 Nutrition imported: G allele associated with increased Body mass index (BMI, minimum, inv-normal transformed) (β=0.040). [GWAS Catalog]
rs17036160 Health risk imported: T allele associated with increased Fasting insulin adjusted for BMI (β=0.072). [GWAS Catalog]
rs1797912 Trait imported: C allele associated with increased Waist-hip index (β=0.030). [GWAS Catalog]
rs2067819 Nutrition imported: G allele associated with increased Triglyceride to HDL cholesterol ratio (β=0.035). [GWAS Catalog]
rs35000407 Trait imported: T allele associated with increased Body mass index (BMI, maximum, inv-normal transformed) (β=0.050). [GWAS Catalog]
rs71304101 Trait imported: A allele associated with increased Triglycerides in large VLDL (β=0.030). [GWAS Catalog]
rs7647481 Health risk imported: A allele associated with increased FABP4 protein levels (β=0.080). [GWAS Catalog]

59 further PPARG variants in the knowledge base have only a brief annotation and are not listed here.

See your own PPARG genotypes
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Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.