TNF Tumour necrosis factor
TNF (Tumour necrosis factor): 4 variants described, covering health risk, drug response.
Which TNF variants does Orviva describe?
- rs1800629 Health risk
- TNF-alpha -308G>A homozygous. Significantly elevated TNF-alpha production; increased risk for autoimmune and inflammatory conditions.
3 further TNF variants in the knowledge base have only a brief annotation and are not listed here.
See your own TNF genotypes
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my TNF variants say about me?”
Upload your 23andMe, AncestryDNA or WeGene raw file → · Ask G2: “What do my TNF variants say about me?”
Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.