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rs3761740 HMGCR

Nutrition

Imported from SNPedia · not individually reviewed Nutrition · Risk / effect allele: ? · dbSNP

What is rs3761740?

rs3761740 is a single-nucleotide polymorphism (SNP) in the HMGCR gene. Each person carries two copies, one from each parent, so a result is reported as a pair of letters such as CT. The table below describes what studies associate with each genotype; the association is statistical, across populations, and is not a diagnosis.

What does each rs3761740 genotype mean?

GenotypeAssociationWhat the evidence saysConfidence

Is rs3761740 on 23andMe and AncestryDNA chips?

Yes — it is genotyped directly on 23andMe V3, 23andMe V4, 23andMe V5. Orviva reads it from a raw-data export without imputation.

Sources

Genetic associations describe risk across populations, not a diagnosis for any one person. Most variants shift risk modestly and act alongside lifestyle, environment and other genes. Consumer DNA chips do not read every position and can be wrong at any single one. For general education only; talk to a clinician or genetic counsellor before acting on anything here, and never change a prescribed medicine without your prescriber.